The clinical research is also our priority. The use of the same database and the consolidation of an image banks and samples will facilitate the implementation of pioneering studies in the cardiovascular field, in turn, will quantify the impact of this initiative on cardiovascular health of the surrounding population .
The research projects carried out in the UDETMA are oriented primarily to:
Currently there are few data on the risk of arteriosclerosis and HCV and indicating more European cohort studies, to assess the presence of arteriosclerosis according to the activity and liver virus damage, or if the antiviral treatment reverses the atheromatous disease while healing HCV infection.
This is a cross-sectional study conducted at the University Hospital Arnau de Vilanova University Hospital Santa María de Lleida (Unit UDETMA and Hepatology Unit) in order to assess the association between HCV and subclinical atherosclerosis.
Vasorum (VV) vasa are physiological blood vessels circulating in parallel by the adventitia of large vessels supplying blood vessels and large caliber. Its primary mission is to provide nutrients and oxygen to the layers that can not make it through the light.
PROJECT TITLE: Influencia de la cirugía bariátrica en las lesiones iniciales de la aterosclerosis: proliferación de vasa vasorum y disfunción endotelial. Mecanismos moleculares implicados
FINANCING ENTITY: FIS
DURATION. FROM: 2016 TO 2019
PRINCIPAL RESEARCHER: J. A. Baena Fustegueras
Among the late complications of diabetes mellitus (DM) are distinguished traditionally two main types of vascular involvement, microangiopathy (retinopathy, nephropathy and neuropathy) and macrovascular (large vessel involvement). We believe that the current classification has determined the conceptual separation between microangiopathic complications and macrovascular and even strands of research in relation to pathogenetic study of different complications.
Atheromatosis is a multifactorial inflammatory process that affects the lining of the arteries, has a longstanding clinical exempt, and manifests itself in very advanced stages causing a cardiovascular event. Psoriasis is an inflammatory disease that may favor the development of atheroma and thus increase the risk of cardiovascular events in this population.
Observational trial promoted by UDETMA and primary care professionals and sponsored by the Diputació of Lleida, in collaboration with Renal Foundation Jaume Arnó. This facility is an adapted bus fully equipped with a broad set of diagnotic tools managed by health care professionals that will be moving around the region of Lleida. It is expected that 3.300 persons a year will be enrolled in the project. Thus, by the end of the reclutation period, around 9.900 people will be evaluated.
A project on the detection of atherosclerotic plaques in patients with human immunodeficiency virus (HIV) has been one of the winners of the third call for research projects on HIV and hepatitis program Gilead Fellowhsip Program 2015. The project will be developed jointly in the Unit Detection and treatment of atherothrombotic diseases (UDETMA) and the HIV Unit of the University Hospital Arnau de Vilanova in Lleida (HUAV).
The NEFRONA project is an observational, prospective, multicenter study of cardiovascular morbidity and mortality in patients with different stages of chronic kidney disease (CKD) distributed throughout the Spanish territory study. The project objectives are:
People with chronic kidney disease (CKD) has deficiency of vitamin D (VD) and high cardiovascular mortality (CV). The VD has CV protective effect but inplicados mechanisms are unknown.
Prospective observational study in 771 patients with CKD-5D, between 18 and 75 years, with no previous CV event, from the multicenter study NEFRONA.
Time Tracking 3 years. For the same itinirante team, vascular study will be conducted: Carotid ultrasound, femoral and brachial and ankle-brachial index (ABI).
The study is designed to: